The green book travel chapters

Cholera is an acute diarrhoeal illness caused by the gram-negative bacterium Vibrio cholerae. Following colonisation of the small bowel, V. cholerae produces an enterotoxin that causes secretion of fluid and electrolytes and leads to painless, watery diarrhoea. Cholera is characterised by the sudden onset of profuse, watery stools with occasional vomiting.

Cholera: the green book, chapter 14 PDF 274 KB 11 pages

Updated: 01 August 2024

Dengue is an acute febrile illness caused by the dengue virus, spread by the bite of an infected Aedes mosquito. Most cases are mild or asymptomatic, but severe, life-threatening disease can occur. It is endemic in more than 100 countries in Africa, the Americas, Eastern Mediterranean, South-east Asia, and Western Pacific region, with sporadic cases occurring in some European countries.

Dengue: the green book, chapter 15a PDF 224 KB 10 pages

Updated: 15 October 2024

Japanese encephalitis (JE) is a mosquito-borne viral encephalitis caused by a flavivirus. It is the leading cause of childhood encephalitis in Asia, with an estimated 68,000 clinical cases per annum (World Health Organization, 2019).

Japanese encephalitis: the green book, chapter 20 PDF 250 KB 7 pages

Updated: 06 February 2024

Tick-borne encephalitis (TBE) is caused by members of the flavivirus family that can affect the central nervous system. Although TBE is most commonly recognised as a meningo-encephalitis, mild febrile illnesses can also occur.

Tick-borne encephalitis: the green book PDF 211 KB 9 pages

Updated: 04 August 2026

Yellow fever is an acute flavivirus infection spread by the bite of an infected mosquito.

In February 2024, this chapter was updated to include new guidance on yellow fever vaccination for individuals with an allergy to egg. Guidance has been added from the Society for Cardiothoracic Surgery in Great Britain and Ireland (SCTS) on thymectomy and cardiac surgery. In March 2024, further updates have been added to the reinforcing immunisation content.

Yellow fever: the green book, chapter 35 PDF 279 KB 15 pages

Updated: 01 March 2024